Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 4/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954629 | 0.84 | ERN1 (0.46) | TYRTRIM24TRIM33ERN1CHRNA7 | |
| SCHEMBL15169263 | 0.82 | CA12 (0.57) | TYRTRIM24TRIM33ERN1CHRNA7 | |
| SCHEMBL10002426 | 0.79 | ESR1 (0.40) | TYRCHRNA7CA12CA1CA2 | |
| SCHEMBL8652359 | 0.79 | LCK (0.41) | TYRCHRNA7CA12CA1CA2 | |
| SCHEMBL27918002 | 0.78 | KEAP1 (0.44) | ERN1PARP1CES2KDM4EALDH1A1 | |
| SCHEMBL12396262 | 0.78 | SRC (0.46) | ERN1PARP1KDM4EALDH1A1HPGD | |
| SCHEMBL1805264 | 0.76 | CES2 (0.50) | CA12CA1CA2ALOX5PTGS2 | |
| SCHEMBL29951029 | 0.76 | TYR (0.43) | TYRTRIM24TRIM33ERN1CHRNA7 | |
| SCHEMBL13365632 | 0.74 | LRRK2 (0.47) | ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL28901717 | 0.74 | TYR (0.42) | TYRTRIM24TRIM33ERN1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |