Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | UNG | P13051 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.37 |
| ▸ | ABAT | P80404 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287843 | 0.85 | KDM4E (0.39) | ERN1KDM4EPTGS2RAB9APARP10 | |
| SCHEMBL30014296 | 0.82 | ALDH1A1 (0.48) | ERN1KDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL436346 | 0.82 | ALDH1A1 (0.48) | ERN1KDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL15651057 | 0.80 | ALDH1A1 (0.57) | ERN1KDM4EPTGS2RAB9APARP10 | |
| SCHEMBL15088224 | 0.80 | MAPT (0.42) | ERN1KDM4EPTGS2ALDH1A1DGAT1 | |
| SCHEMBL5087817 | 0.80 | CES2 (0.45) | ERN1KDM4EALDH1A1DGAT1KMT2A | |
| SCHEMBL29957499 | 0.80 | KDM4E (0.57) | ERN1KDM4EPTGS2RAB9APARP10 | |
| SCHEMBL29954629 | 0.80 | ERN1 (0.46) | ERN1KDM4EALDH1A1TSHRKMT2A | |
| SCHEMBL11287845 | 0.79 | KDM4E (0.38) | KDM4EPTGS2RAB9APARP10PARP3 | |
| SCHEMBL1800318 | 0.78 | PARP10 (0.44) | ERN1KDM4EPTGS2RAB9APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4372091-A2 | COMPOSITIONS AND METHODS FOR EDITING NUCLEIC ACIDS IN CELLS UTILIZING OLIGONUCLEOTIDES | Woolf, Tod M. (US) | 2024-05-22 | — | — | EP | disclosed |
| EP-3230445-B1 | COMPOSITIONS AND METHODS FOR EDITING NUCLEIC ACIDS IN CELLS UTILIZING OLIGONUCLEOTIDES | WOOLF TOD M (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-4023228-A1 | GENOME EDITING OLIGONUCLEOTIDE WITHOUT PROGRAMMABLE NUCLEASES | Woolf, Tod M. (US) | 2022-07-06 | — | — | EP | disclosed |
| US-20210395729-A1 | Compositions and methods for Editing Nucleic Acids in Cells Utilizing Oligonucleotides | ETAGEN PHARMA, INC. | 2021-12-23 | — | — | US | disclosed |
| US-20190300872-A1 | Improved Methods of Genome Editing with and without Programmable Nucleases | WOOLF TOD M (US) | 2019-10-03 | — | — | US | disclosed |
| EP-3230445-A2 | COMPOSITIONS AND METHODS FOR EDITING NUCLEIC ACIDS IN CELLS UTILIZING OLIGONUCLEOTIDES | Woolf, Tod M. (US) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094845-A2 | COMPOSITIONS AND METHODS FOR EDITING NUCLEIC ACIDS IN CELLS UTILIZING OLIGONUCLEOTIDES | WOOLF TOD M (US) | 2016-06-16 | — | — | WO | disclosed |