Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 9/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12538526 | 1.00 | L3MBTL1 (0.46) | L3MBTL1CYP1A2CYP2C19CYP2C9FAAH | |
| SCHEMBL3316374 | 0.92 | L3MBTL1 (0.44) | L3MBTL1CYP1A2CYP2C19CYP2C9FAAH | |
| SCHEMBL29952625 | 0.92 | L3MBTL1 (0.44) | L3MBTL1CYP1A2CYP2C19CYP2C9FAAH | |
| SCHEMBL3789201 | 0.88 | CYP1A2 (0.52) | CYP1A2CYP2C19CYP2C9MCHR1PTPN1 | |
| SCHEMBL9945992 | 0.85 | L3MBTL1 (0.47) | L3MBTL1CYP1A2CYP2C19CYP2C9FAAH | |
| SCHEMBL29957026 | 0.85 | L3MBTL1 (0.50) | L3MBTL1CYP1A2CYP2C19TDP1CYP2D6 | |
| SCHEMBL954824 | 0.85 | L3MBTL1 (0.50) | L3MBTL1CYP1A2CYP2C19TDP1CYP2D6 | |
| SCHEMBL15430194 | 0.83 | MEN1 (0.49) | CYP1A2CYP2C19CYP2C9MCHR1MEN1 | |
| SCHEMBL15430193 | 0.81 | LMNA (0.51) | CYP1A2CYP2C19CYP2C9MCHR1MEN1 | |
| SCHEMBL9945959 | 0.81 | L3MBTL1 (0.42) | L3MBTL1CYP1A2CYP2C19CYP2C9FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |