Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952625 | 0.89 | L3MBTL1 (0.44) | L3MBTL1PDE4DTDP1CYP1A2CYP2C19 | |
| SCHEMBL3316374 | 0.89 | L3MBTL1 (0.44) | L3MBTL1PDE4DTDP1CYP1A2CYP2C19 | |
| SCHEMBL9945925 | 0.87 | L3MBTL1 (0.49) | L3MBTL1TDP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL29954630 | 0.81 | L3MBTL1 (0.46) | L3MBTL1TDP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL12538526 | 0.81 | L3MBTL1 (0.46) | L3MBTL1TDP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL3785252 | 0.79 | MCHR1 (0.44) | CYP1A2CYP2C19MCHR1CYP2A6HTR2C | |
| SCHEMBL9945992 | 0.79 | L3MBTL1 (0.47) | L3MBTL1TDP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL9945939 | 0.78 | HPGD (0.38) | L3MBTL1PDE4DTDP1CYP1A2CYP2C19 | |
| SCHEMBL8216509 | 0.75 | L3MBTL1 (0.50) | L3MBTL1PDE4DTDP1CYP1A2CYP2C19 | |
| SCHEMBL29635826 | 0.75 | L3MBTL1 (0.69) | L3MBTL1TDP1CYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | L3MBTL1 4393/4885PDE4D 611/4885TDP1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.