Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953449 | 0.94 | FEN1 (0.38) | DYRK1ANOS1NOS2NOS3CNR1 | |
| SCHEMBL29953370 | 0.83 | APOL1 (0.35) | HTR2AHTR2CKCNH2 | |
| SCHEMBL29957613 | 0.83 | NOS2 (0.40) | DYRK1ANOS1NOS2NOS3HTR2A | |
| SCHEMBL29951956 | 0.83 | TRIM24 (0.41) | DYRK1AGAA | |
| SCHEMBL29956616 | 0.83 | MEN1 (0.41) | DYRK1AOPRL1SLC6A4GSK3B | |
| SCHEMBL29955075 | 0.82 | PIM1 (0.45) | DYRK1ASLC6A4HTR2CHTT | |
| SCHEMBL29954538 | 0.81 | FFAR2 (0.34) | DYRK1AFFAR2 | |
| SCHEMBL29951429 | 0.81 | APOL1 (0.33) | — | |
| SCHEMBL29954328 | 0.81 | AR (0.35) | NOS1NOS2NOS3FFAR2 | |
| SCHEMBL29950867 | 0.80 | ALDH1A1 (0.53) | DYRK1AGAAHTTABCB1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |