Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | LPL | P06858 | 6/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16687427 | 0.94 | ENPP2 (0.59) | ENPP2CA2CA1LPLLIPG | |
| SCHEMBL29956136 | 0.94 | ENPP2 (0.59) | ENPP2CA2CA1LPLLIPG | |
| SCHEMBL28784898 | 0.82 | CA2 (0.76) | ENPP2CA2CA1LPLLIPG | |
| SCHEMBL3039135 | 0.82 | CA2 (0.52) | ENPP2CA2CA1CA12CA3 | |
| SCHEMBL14756814 | 0.79 | CA1 (0.50) | CA2CA1LPLLIPGF11 | |
| SCHEMBL29954651 | 0.77 | CA1 (0.66) | CA2CA1LPLLIPGHSD17B10 | |
| SCHEMBL15985354 | 0.75 | MAPT (0.49) | CA2CA1LPLLIPGHSD17B10 | |
| SCHEMBL13667343 | 0.75 | CA2 (0.73) | ENPP2CA2CA1LPLLIPG | |
| SCHEMBL13525455 | 0.75 | CA2 (0.50) | ENPP2CA2CA1CA12CA3 | |
| SCHEMBL112402 | 0.75 | LPL (0.61) | ENPP2CA2CA1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |