Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951207 | 0.88 | GSK3B (0.48) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL3198006 | 0.79 | LMNA (0.51) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL4824528 | 0.77 | LMNA (0.40) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL4824535 | 0.77 | LMNA (0.40) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL28460398 | 0.76 | PIM1 (0.46) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL29951828 | 0.76 | PIM1 (0.46) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL16920112 | 0.76 | PIM1 (0.46) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL29951788 | 0.75 | HPGD (0.44) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL29955514 | 0.72 | RXFP1 (0.58) | LMNAPIM1PIM3GSK3BPRNP | |
| SCHEMBL28197841 | 0.72 | LMNA (0.41) | LMNAHPGDPIM1PIM3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |