Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28197840 | 0.83 | KEAP1 (0.41) | LMNAHPGDCHUKJAK2BAZ2B | |
| SCHEMBL28197177 | 0.83 | LMNA (0.45) | LMNAHPGDSIRT1CHUKMAPT | |
| SCHEMBL28197843 | 0.81 | ALDH1A1 (0.49) | HPGDCHUKMAPTHSD17B10HAVCR2 | |
| SCHEMBL28197180 | 0.79 | AHR (0.41) | LMNAHPGDGSK3BMAPTHSD17B10 | |
| SCHEMBL3198006 | 0.75 | LMNA (0.51) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL28460398 | 0.72 | PIM1 (0.46) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL29951828 | 0.72 | PIM1 (0.46) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL16920112 | 0.72 | PIM1 (0.46) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL29951788 | 0.72 | HPGD (0.44) | LMNAHPGDPIM1PIM3GSK3B | |
| SCHEMBL29954657 | 0.72 | LMNA (0.44) | LMNAHPGDPIM1PIM3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573335-A | A kind of hand oxazole alkyl compound and preparation method thereof | 安徽师范大学 | 2018-01-12 | — | — | CN | disclosed |