Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584978 | 0.83 | CDK4 (0.43) | ALDH1A1 | |
| SCHEMBL4154671 | 0.83 | LPL (0.44) | SGK1CAMKK2TTR | |
| SCHEMBL1356439 | 0.80 | ACE2 (0.50) | ADRB3ADRB1SGK1CAMKK2ALDH1A1 | |
| SCHEMBL23124017 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TTR | |
| SCHEMBL17756314 | 0.78 | CSNK2A1 (0.47) | ADRB3ADRB1SGK1CAMKK2ALDH1A1 | |
| SCHEMBL311797 | 0.78 | CA12 (0.50) | ADRB3ADRB1SGK1CAMKK2ALDH1A1 | |
| SCHEMBL4167084 | 0.77 | MAPT (0.47) | ADRB3ADRB1SGK1CAMKK2ALDH1A1 | |
| SCHEMBL27888038 | 0.77 | GABRA1 (0.56) | ADRB3ADRB1SGK1CAMKK2AKR1C2 | |
| SCHEMBL23486432 | 0.77 | SGK1 (0.44) | ADRB3ADRB1SGK1CAMKK2ALDH1A1 | |
| SCHEMBL525582 | 0.77 | ALDH1A1 (0.50) | ADRB3ADRB1SGK1CAMKK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |