Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.43 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257861 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL12419272 | 0.90 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL12260587 | 0.78 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL12330749 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL23271179 | 0.75 | LOXL2 (0.34) | MAPT | |
| SCHEMBL20064626 | 0.75 | ALDH1A1 (0.53) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL11637093 | 0.73 | ALDH1A1 (0.55) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL7948373 | 0.73 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL806348 | 0.72 | ALDH1A1 (0.54) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL4130976 | 0.72 | PSMB8 (0.46) | ALDH1A1LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |