Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671629 | 1.00 | KIF11 (0.49) | KIF11KDM4EALDH1A1LMNAHTT | |
| SCHEMBL29955256 | 0.88 | CREBBP (0.48) | KIF11KDM4EALDH1A1LMNAHTT | |
| SCHEMBL5960261 | 0.81 | RAB9A (0.36) | KIF11KDM4EALDH1A1LMNAHTT | |
| SCHEMBL6421763 | 0.80 | KIF11 (0.53) | KIF11KDM4EALDH1A1LMNAHTT | |
| SCHEMBL30460215 | 0.80 | KDM4E (0.61) | KIF11KDM4EALDH1A1LMNAHTT | |
| SCHEMBL5881610 | 0.80 | KDM4E (0.61) | KIF11KDM4EALDH1A1LMNAHTT | |
| SCHEMBL20875018 | 0.78 | KIF11 (0.51) | KIF11KDM4EALDH1A1LMNAHTT | |
| SCHEMBL6424303 | 0.77 | KIF11 (0.50) | KIF11KDM4EALDH1A1LMNAHTT | |
| SCHEMBL28415588 | 0.77 | EIF4A3 (0.55) | KIF11KDM4EALDH1A1LMNAHTT | |
| SCHEMBL15046545 | 0.76 | KIF11 (0.53) | KIF11KDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |