Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671629 | 0.81 | KIF11 (0.49) | RAB9AKDM4EALDH1A1HTTLMNA | |
| SCHEMBL29954766 | 0.81 | KIF11 (0.49) | RAB9AKDM4EALDH1A1HTTLMNA | |
| SCHEMBL19463191 | 0.79 | GABRA1 (0.36) | RAB9AGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL29955256 | 0.71 | CREBBP (0.48) | RAB9AKDM4EALDH1A1HTTLMNA | |
| SCHEMBL5016542 | 0.69 | KDM4E (0.37) | RAB9AKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL8479941 | 0.68 | GABRA1 (0.47) | RAB9AKDM4EALDH1A1HTTLMNA | |
| SCHEMBL20612118 | 0.65 | RAB9A (0.48) | RAB9AKDM4EALDH1A1HTTLMNA | |
| SCHEMBL11888497 | 0.65 | ALDH1A1 (0.53) | KDM4EALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL3359679 | 0.65 | HRH3 (0.58) | RAB9AKDM4EALDH1A1HTTLMNA | |
| SCHEMBL1615765 | 0.64 | GABRA1 (0.46) | RAB9AKDM4EALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682553-A1 | THIENOPYRAZOLES | Aventis Pharmaceuticals Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005026175-A1 | THIENOPYRAZOLES | AVENTIS PHARMACEUTICALS INC. (US) | 2005-03-24 | — | — | WO | disclosed |