Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12847220 | 0.88 | MGLL (0.40) | MGLLPDE2ASCN8ASCN10ARXFP1 | |
| SCHEMBL29952234 | 0.88 | MGLL (0.40) | MGLLPDE2ASCN8ASCN10ARXFP1 | |
| SCHEMBL2463852 | 0.82 | ENPP2 (0.47) | MGLLKDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL29954889 | 0.82 | ENPP2 (0.47) | MGLLKDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL25368443 | 0.81 | MGLL (0.42) | MGLLPDE2ASCN8ASCN10ARXFP1 | |
| SCHEMBL4618735 | 0.81 | HTR2A (0.41) | MGLLPDE2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL29953373 | 0.78 | CYP2C19 (0.51) | MGLLPDE2ASCN8ASCN10ARXFP1 | |
| SCHEMBL15009911 | 0.78 | CYP2C19 (0.51) | MGLLPDE2ASCN8ASCN10ARXFP1 | |
| SCHEMBL26978410 | 0.77 | ALDH1A1 (0.55) | SCN8ASCN10ARXFP1KDM4EUSP2 | |
| SCHEMBL957598 | 0.77 | ALDH1A1 (0.41) | PDE2ASCN8ASCN10ARXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |