Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19384201 | 0.86 | ENPP2 (0.40) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL3784993 | 0.84 | ENPP2 (0.48) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL32669062 | 0.81 | ENPP2 (0.42) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL3783525 | 0.81 | HDAC4 (0.51) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL3786808 | 0.81 | HDAC4 (0.47) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL3784746 | 0.79 | KMO (0.53) | ENPP2KDM4EALDH1A1MGLLHDAC4 | |
| SCHEMBL14188120 | 0.78 | PARP1 (0.51) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL27248261 | 0.78 | ENPP2 (0.41) | ENPP2KDM4EMGLLCA4CA6 | |
| SCHEMBL22325842 | 0.76 | DRD2 (0.46) | ALDH1A1CA5ACA14CA5BCA2 | |
| SCHEMBL1624290 | 0.73 | ENPP2 (0.45) | ENPP2KDM4EALDH1A1MGLLCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |