Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564080 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBAGTR1ABCG2PDK2 | |
| SCHEMBL4888374 | 0.87 | POLB (0.39) | SMN1; SMN2POLBABCG2PDK2NPC1 | |
| SCHEMBL9257119 | 0.84 | POLB (0.40) | SMN1; SMN2POLBABCG2PDK2NPC1 | |
| SCHEMBL14169541 | 0.83 | POLB (0.34) | SMN1; SMN2POLBAGTR1 | |
| SCHEMBL30743612 | 0.79 | ABCG2 (0.55) | SMN1; SMN2POLBAGTR1ABCG2NPC1 | |
| SCHEMBL16370823 | 0.78 | AGTR1 (0.43) | SMN1; SMN2POLBAGTR1ABCG2NPC1 | |
| SCHEMBL9429714 | 0.78 | ABCG2 (0.36) | SMN1; SMN2POLBAGTR1ABCG2NPC1 | |
| SCHEMBL4990435 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2POLBABCG2NPC1RAB9A | |
| SCHEMBL8402419 | 0.77 | POLB (0.40) | SMN1; SMN2POLBAGTR1ABCG2NPC1 | |
| SCHEMBL9033772 | 0.77 | AGTR1 (0.41) | SMN1; SMN2POLBAGTR1ABCG2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |