Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955120 | 0.84 | NPC1 (0.51) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL29951366 | 0.83 | HIF1A (0.45) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL15330532 | 0.82 | MAPK14 (0.43) | NPC1RAB9ASMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL15332981 | 0.81 | NPBWR1 (0.41) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL15331277 | 0.80 | NPC1 (0.46) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL31632786 | 0.76 | NR3C1 (0.49) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL29955468 | 0.76 | KMT2A (0.43) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL15330680 | 0.75 | MAPT (0.51) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL15332784 | 0.74 | PTGS2 (0.36) | NPBWR1MCHR1POLBL3MBTL1 | |
| SCHEMBL3039672 | 0.74 | MAPT (0.61) | NPC1RAB9AHPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |