Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951951 | 1.00 | ABCC4 (0.37) | ABCC4MAPTDDAH1CYP2C19SLC6A2 | |
| SCHEMBL2805648 | 0.86 | MAPT (0.43) | ABCC4MAPTDDAH1CYP2C19SLC6A2 | |
| SCHEMBL3751301 | 0.85 | SLC6A3 (0.41) | CYP2C19SLC6A2SLC6A4BLMSLC6A3 | |
| SCHEMBL31153192 | 0.85 | MAPT (0.47) | ABCC4MAPTDDAH1CYP2C19SLC6A2 | |
| SCHEMBL31153188 | 0.83 | MAPT (0.50) | ABCC4MAPTDDAH1SLC6A2SLC6A4 | |
| SCHEMBL28680597 | 0.83 | MAPT (0.50) | ABCC4MAPTDDAH1SLC6A2SLC6A4 | |
| SCHEMBL10280871 | 0.83 | MAPT (0.50) | ABCC4MAPTDDAH1SLC6A2SLC6A4 | |
| SCHEMBL9776472 | 0.78 | — | — | |
| SCHEMBL4452846 | 0.78 | GPR84 (0.37) | ABCC4MAPTCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL18833177 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |