Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63074 | 1.00 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL1101791 | 0.83 | KDM4E (0.56) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL27158631 | 0.73 | MAP2K4 (0.53) | KDM4EGAAALDH1A1HPGDMAP2K4 | |
| SCHEMBL476840 | 0.72 | KDM4E (0.39) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL276725 | 0.71 | KDM4E (0.58) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL25346553 | 0.71 | KMT2A (0.39) | KDM4ELRRK2CDK2AURKA | |
| SCHEMBL27728321 | 0.71 | RARG (0.50) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL1672674 | 0.70 | IDO1 (0.78) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| Hydrochloric Acid SCHEMBL28343698 | 0.70 | KDM4E (0.56) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL29481432 | 0.69 | PDPK1 (1.00) | KDM4EGAAPDPK1CYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |