SCHEMBL276725

SCHEMBL276725

Oc1n[nH]c2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.58
GAA P10253 2/20 0.58
PDPK1 O15530 1/20 0.58
CYP3A4 P08684 1/20 0.58
IDO1 P14902 4/20 0.54
ALDH1A1 P00352 2/20 0.54
ALPL P05186 1/20 0.54
HPGD P15428 1/20 0.54
TTK P33981 1/20 0.54
MAPK10 P53779 1/20 0.54
MAP2K4 P45985 2/20 0.50
CYP1A2 P05177 1/20 0.48
YTHDC1 Q96MU7 1/20 0.47
STAT3 P40763 1/20 0.47
HIF1A Q16665 1/20 0.47
LRRK2 Q5S007 2/20 0.46
NPC1 O15118 1/20 0.46
TP53 P04637 1/20 0.46
RAB9A P51151 1/20 0.46
CCNA2 P20248 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9041896 0.83 CYP1A2 (0.61) KDM4EGAAPDPK1CYP3A4IDO1
SCHEMBL1672674 0.75 IDO1 (0.78) KDM4EGAAPDPK1CYP3A4IDO1
SCHEMBL9407409 0.73 KDM4E (0.60) KDM4EGAAPDPK1CYP3A4IDO1
SCHEMBL29481432 0.73 PDPK1 (1.00) KDM4EGAAPDPK1CYP3A4IDO1
SCHEMBL18878 0.73 PDPK1 (1.00) KDM4EGAAPDPK1CYP3A4IDO1
SCHEMBL765469 0.73 ATM (0.57) KDM4EGAAALDH1A1CYP1A2MAPK1
SCHEMBL4200287 0.73 IDO1 (0.71) KDM4EGAAPDPK1IDO1ALDH1A1
SCHEMBL962678 0.71 KDM4E (0.58) KDM4EGAAPDPK1CYP3A4IDO1
SCHEMBL61457 0.71 KDM4E (0.58) KDM4EGAAPDPK1CYP3A4IDO1
SCHEMBL1012344 0.71 KDM4E (0.58) KDM4EGAAPDPK1CYP3A4IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059278-A Core-shell foaming agent, micro-foaming material, and preparation methods and applications thereof 中国石油化工股份有限公司 2025-05-30 CN claimed
CN-118994533-A Polycarbonate polyurethane material, polycarbonate/polyamide composite material containing same and preparation and application thereof 中国石油化工股份有限公司 2024-11-22 CN claimed
CN-112226058-B Antistatic heat conduction material and preparation method and application thereof 中国石油化工股份有限公司 2023-07-04 CN claimed
CN-115279749-A SHP2 inhibitor and composition and application thereof 贝达药业股份有限公司 2022-11-01 CN claimed
EP-3901153-A1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS Janssen Pharmaceutica NV (BE) 2021-10-27 EP claimed
US-20210284641-A1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2021-09-16 US claimed
CN-107835814-B Azabenzimidazoles and their use as AMPA receptor modulators 詹森药业有限公司 2021-07-23 CN claimed
EP-3288940-B9 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2021-07-21 EP claimed
EP-3288940-B1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2021-02-24 EP claimed
CN-112226058-A Antistatic heat conduction material and preparation method and application thereof 中国石油化工股份有限公司 2021-01-15 CN claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007071686-A1 COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER L'ORÉAL (FR) 2007-06-28 WO claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses L'OREAL (FR) 2004-11-25 US claimed
EP-1428510-A1 Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use L'OREAL (FR) 2004-06-16 EP claimed
CN-1218472-A Pharmaceutically useful compounds ASTRA PHARMA PROD (GB) 1999-06-02 CN claimed
EP-0246623-B1 SILVER HALIDE EMULSIONS AND METHOD FOR THE PREPARATION THEREOF Fuji Photo Film Co., Ltd. (JP) 1992-08-26 EP claimed
US-4168953-A Oxidation hair dyes based upon tetraaminopyrimidine developers and monohydroxyindazole couplers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-09-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210284641-A1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS GRIN1, GRIN2B, GRIN3A KDM4E 1436/4885GAA 1903/4885PDPK1 3115/4885
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses KRT18, CDC73, PYCR1 KDM4E 1620/4885GAA 4874/4885PDPK1 2330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.