Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 4/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.34 |
| ▸ | WNT3A | P56704 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954805 | 0.72 | KDM4E (0.52) | KDM4ESTAT3HIF1AGAAPDPK1 | |
| SCHEMBL63074 | 0.72 | KDM4E (0.52) | KDM4ESTAT3HIF1AGAAPDPK1 | |
| SCHEMBL8784 | 0.72 | IDO1 (0.41) | CYP3A4CYP1A2IDO1HPGDMAPT | |
| SCHEMBL4434307 | 0.71 | CYP3A4 (0.44) | CYP3A4NPC1LMNARAB9A | |
| SCHEMBL11969988 | 0.69 | KIF11 (0.47) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14635056 | 0.69 | KIF11 (0.47) | KDM4ECYP3A4CYP1A2ALDH1A1HPGD | |
| SCHEMBL535000 | 0.69 | KIF11 (0.47) | KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8533 | 0.69 | ADORA2A (0.33) | — | |
| SCHEMBL1101791 | 0.69 | KDM4E (0.56) | KDM4ESTAT3HIF1AGAAPDPK1 | |
| SCHEMBL119711 | 0.68 | TRPV6 (0.39) | HIF1AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161359-A | Novel 4-morpholinyl thieno [3,2-d ] pyrimidine compound containing acrylamide structure and application thereof | 辽宁大学 | 2024-12-20 | — | — | CN | disclosed |
| US-9997728-B2 | Organometallic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-06-12 | — | — | US | disclosed |
| EP-2706064-B1 | Organometallic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO LTD (KR) | 2016-11-09 | — | — | EP | disclosed |
| US-20160293868-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO LTD (KR) | 2016-10-06 | — | — | US | disclosed |
| US-9373798-B2 | Organometallic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-06-21 | — | — | US | disclosed |
| US-8987280-B2 | Pyrazolopyrimidine PI3K inhibitor compounds and methods of use | GENENTECH, INC. (US) | 2015-03-24 | — | — | US | disclosed |
| EP-2252616-B1 | PYRAZOLOPYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-20140070180-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-03-13 | — | — | US | disclosed |
| EP-2706064-A1 | Organometallic compound and organic light-emitting device including the same | Samsung Display Co., Ltd. (KR) | 2014-03-12 | — | — | EP | disclosed |
| EP-2411398-A1 | METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20110172216-A1 | PYRAZOLOPYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| CN-101981037-A | Pyrazolopyrimidine PI3K inhibitor compounds and methods of use | GENENTECH INC | 2011-02-23 | — | — | CN | disclosed |
| EP-2252616-A1 | PYRAZOLOPYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | Genentech, Inc. (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2010110782-A1 | METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |
| WO-2009097446-A1 | PYRAZOLOPYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2009-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160293868-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | LAGE3, PPOX, CRY1 | KDM4E 1317/4885STAT3 3597/4885HIF1A 3489/4885 |
| US-20110172216-A1 | PYRAZOLOPYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | PIK3CA, PIK3CD, PI4KA | KDM4E 3604/4885STAT3 1199/4885HIF1A 3224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.