Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1956935 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1FFAR4FFAR1TRPV4 | |
| SCHEMBL1605954 | 0.84 | HTR2A (0.41) | KDM4EALDH1A1FFAR4FFAR1TRPV4 | |
| SCHEMBL3748043 | 0.80 | TRPV4 (0.38) | KDM4EALDH1A1FFAR4FFAR1TRPV4 | |
| SCHEMBL15428101 | 0.80 | ALDH1A1 (0.39) | KDM4EALDH1A1ERN1PTPN1 | |
| SCHEMBL16962133 | 0.80 | FFAR4 (0.38) | FFAR4FFAR1TRPV4MAOAMAOB | |
| SCHEMBL7195384 | 0.78 | RAD51 (0.40) | ALDH1A1 | |
| SCHEMBL21505592 | 0.77 | TRPV4 (0.43) | ALDH1A1TRPV4ERN1CYP11B1CYP11B2 | |
| SCHEMBL23017989 | 0.77 | KDM4E (0.42) | KDM4EFFAR4FFAR1CYP11B1CYP11B2 | |
| Water SCHEMBL28915146 | 0.76 | ERN1 (0.45) | KDM4EALDH1A1ERN1PTPN1 | |
| SCHEMBL4973143 | 0.76 | ERN1 (0.52) | ALDH1A1ERN1PTPN1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |