SCHEMBL16962133

SCHEMBL16962133

N#Cc1ccc(F)cc1[CH]O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.38
FFAR1 O14842 1/20 0.38
TRPV4 Q9HBA0 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
CYP11B2 P19099 3/20 0.37
CYP11B1 P15538 2/20 0.37
AR P10275 1/20 0.36
P4HB P07237 2/20 0.35
NFE2L2 Q16236 2/20 0.33
POLB P06746 1/20 0.33
CHRM4 P08173 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3748043 0.80 TRPV4 (0.38) FFAR4FFAR1TRPV4MAOAMAOB
SCHEMBL1956935 0.80 KDM4E (0.39) FFAR4FFAR1TRPV4MAOAMAOB
SCHEMBL29954838 0.80 KDM4E (0.39) FFAR4FFAR1TRPV4MAOAMAOB
SCHEMBL27720947 0.79 FFAR4 (0.36) FFAR4FFAR1TRPV4MAOAMAOB
SCHEMBL16961102 0.78 CA2 (0.38) TRPV4
SCHEMBL23017989 0.77 KDM4E (0.42) FFAR4FFAR1CYP11B2CYP11B1AR
SCHEMBL16954722 0.76 AR (0.39) FFAR1MAOAMAOBARPOLB
SCHEMBL16955082 0.76 MAOB (0.42) MAOAMAOBCYP11B2CYP11B1POLB
SCHEMBL16958095 0.76 VCAM1 (0.44) TRPV4MAOAMAOBARPOLB
SCHEMBL16960046 0.76 AR (0.47) CYP11B2CYP11B1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed