Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.31 |
| ▸ | TTR | P02766 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890521 | 0.82 | TSHR (0.39) | TSHRHTR2AHTR2CHTR2BCA2 | |
| SCHEMBL29636287 | 0.82 | TSHR (0.39) | TSHRHTR2AHTR2CHTR2BCA2 | |
| SCHEMBL29427148 | 0.77 | ALDH1A1 (0.38) | TSHRHTR2AHTR2CHTR2BCA2 | |
| SCHEMBL15968820 | 0.77 | ALDH1A1 (0.38) | TSHRHTR2AHTR2CHTR2BCA2 | |
| SCHEMBL29956860 | 0.76 | ACHE (0.32) | HTR2BCA2LPLLIPGTUBB4A | |
| SCHEMBL29957805 | 0.76 | PPARA (0.36) | TSHRHTR2AHTR2CHTR2BCA2 | |
| SCHEMBL29957060 | 0.75 | ENPP2 (0.48) | TSHRCA2LPLLIPGENPP2 | |
| SCHEMBL29957988 | 0.74 | ENPP2 (0.56) | CA2LPLLIPGENPP2CA1 | |
| SCHEMBL29951974 | 0.73 | KDM4E (0.40) | TSHRENPP2 | |
| SCHEMBL23743 | 0.72 | ENPP2 (0.48) | TSHRCA2LPLLIPGENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |