Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14825161 | 0.93 | TSHR (0.77) | TSHRKDM4ELMNATP53ALOX15 | |
| SCHEMBL11713011 | 0.91 | LMNA (0.84) | TSHRKDM4ELMNATP53ALOX15 | |
| SCHEMBL2678029 | 0.87 | TSHR (0.68) | TSHRKDM4ELMNATP53ALOX15 | |
| SCHEMBL11488934 | 0.86 | MEN1 (0.62) | TSHRKDM4ELMNATP53ALOX15 | |
| SCHEMBL29944105 | 0.86 | MEN1 (0.62) | TSHRKDM4ELMNATP53ALOX15 | |
| SCHEMBL487595 | 0.85 | HSP90AA1 (0.64) | TSHRKDM4ELMNATP53ALOX15 | |
| SCHEMBL24508969 | 0.84 | P2RX7 (0.60) | TSHRKDM4ELMNATP53ALOX15 | |
| SCHEMBL2740465 | 0.83 | TP53 (0.68) | TSHRKDM4ELMNATP53ALOX15 | |
| SCHEMBL1042677 | 0.83 | KDM4E (1.00) | TSHRKDM4ELMNATP53ALOX15 | |
| SCHEMBL22767344 | 0.83 | HPGD (0.58) | TSHRKDM4ELMNATP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489085-B1 | RIGID-ROD POLYMERS | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2005-12-07 | — | — | EP | claimed |
| US-5565543-A | Rigid-rod polymers | MAXDEM INCORPORATED (US) | 1996-10-15 | — | — | US | claimed |
| EP-0489085-A4 | RIGID-ROD POLYMERS | MAXDEM INC (US) | 1992-08-05 | — | — | EP | claimed |
| EP-0489085-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1992-06-10 | — | — | EP | claimed |
| WO-1991002764-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1991-03-07 | — | — | WO | claimed |
| US-20230110003-A1 | PIPERIDINE DERIVATIVES AND COMPOSITIONS FOR THE INHIBITION OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) | Valo Health, LLC | 2023-04-13 | — | — | US | disclosed |
| US-11479564-B2 | Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT) | VALO HEALTH, INC. (US) | 2022-10-25 | — | — | US | disclosed |
| EP-0489085-B1 | RIGID-ROD POLYMERS | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2005-12-07 | — | — | EP | disclosed |
| EP-1352731-A2 | Method of orienting polymer molecules | MISSISSIPPI POLYMER TECHNOLOGIES, INC. (US) | 2003-10-15 | — | — | EP | disclosed |
| EP-0629217-B1 | RIGID-ROD POLYMERS | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-0599886-B1 | MACROMONOMERS HAVING REACTIVE END GROUPS | MISSISSIPPI POLYMER TECH INC (US) | 2001-03-21 | — | — | EP | disclosed |
| EP-0646143-B1 | MACROMONOMERS HAVING REACTIVE SIDE GROUPS | MAXDEM INC (US) | 2000-10-18 | — | — | EP | disclosed |
| EP-0629217-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1994-12-21 | — | — | EP | disclosed |
| EP-0599886-A1 | MACROMONOMERS HAVING REACTIVE END GROUPS | MAXDEM INCORPORATED (US) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993018077-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1993-09-16 | — | — | WO | disclosed |
| WO-1993018076-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1993-09-16 | — | — | WO | disclosed |
| WO-1993004099-A1 | MACROMONOMERS HAVING REACTIVE END GROUPS | MAXDEM INCORPORATED (US) | 1993-03-04 | — | — | WO | disclosed |
| EP-0489085-A4 | RIGID-ROD POLYMERS | MAXDEM INC (US) | 1992-08-05 | — | — | EP | disclosed |
| EP-0489085-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1992-06-10 | — | — | EP | disclosed |
| WO-1991002764-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1991-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230110003-A1 | PIPERIDINE DERIVATIVES AND COMPOSITIONS FOR THE INHIBITION OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) | NAMPT, NAPRT, NNMT | TSHR 3065/4885KDM4E 2054/4885LMNA 1753/4885 |
| US-11479564-B2 | Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT) | NAMPT, NAPRT, NNMT | TSHR 3065/4885KDM4E 2054/4885LMNA 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.