Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326214 | 1.00 | GPR3 (0.42) | GPR3WDR5ABL1LMNANR1H2 | |
| SCHEMBL28961819 | 0.87 | GPR3 (0.43) | GPR3WDR5ABL1MAPTEPHX2 | |
| SCHEMBL257822 | 0.81 | GPR3 (0.42) | GPR3ABL1MAPTEPHX2L3MBTL1 | |
| SCHEMBL29957379 | 0.81 | GPR3 (0.42) | GPR3ABL1LMNAMAPTEPHX2 | |
| SCHEMBL3993839 | 0.80 | FFAR4 (0.41) | GPR3ABL1FFAR4 | |
| SCHEMBL29554405 | 0.80 | FFAR4 (0.41) | GPR3ABL1FFAR4 | |
| SCHEMBL320667 | 0.79 | TUBB4A (0.46) | GPR3ABL1FFAR4 | |
| SCHEMBL29956393 | 0.79 | TUBB4A (0.46) | GPR3ABL1FFAR4 | |
| SCHEMBL24445841 | 0.78 | GPR3 (0.48) | GPR3WDR5LMNAMAPTEPHX2 | |
| SCHEMBL769093 | 0.78 | GPR3 (0.42) | GPR3ABL1MAPTEPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |