Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15959092 | 0.83 | CA3 (0.46) | GPR3AURKATPX2WDR5MAPT | |
| SCHEMBL13250517 | 0.83 | GPR3 (0.46) | GPR3AURKATPX2WDR5MAPT | |
| SCHEMBL2097133 | 0.83 | APP (0.49) | GPR3AURKATPX2WDR5MAPT | |
| SCHEMBL326580 | 0.81 | GPR3 (0.44) | GPR3AURKATPX2WDR5MAPT | |
| SCHEMBL31286071 | 0.81 | ALDH1A1 (0.55) | GPR3WDR5MAPTEPHX2KIF11 | |
| SCHEMBL1024889 | 0.81 | ALDH1A1 (0.55) | GPR3WDR5MAPTEPHX2KIF11 | |
| SCHEMBL13841330 | 0.81 | GPR3 (0.45) | GPR3AURKATPX2WDR5MAPT | |
| SCHEMBL966803 | 0.81 | AKR1C2 (0.45) | GPR3AURKATPX2WDR5MAPT | |
| SCHEMBL6003178 | 0.81 | GPR3 (0.44) | GPR3AURKATPX2WDR5MAPT | |
| SCHEMBL3711415 | 0.81 | WDR5 (0.44) | GPR3AURKATPX2WDR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001336-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | Shin-Etsu Chemical Co., Ltd. (JP) | 2022-05-25 | — | — | EP | disclosed |
| CN-104736535-A | Heterocyclic modulators of hif activity for treatment of disease | JONES PHILIP | 2015-06-24 | — | — | CN | disclosed |
| CN-101765596-B | Inhibitors of hypoxia inducible factor (HIF) useful for treating hyper-proliferative disorders and diseases associated with angiogenesis | BAYER IP GMBH | 2015-04-29 | — | — | CN | disclosed |
| CN-101765596-A | Inhibitors of hypoxia inducible factor (HIF) useful for treating hyper-proliferative disorders and diseases associated with angiogenesis | BAYER HEALTHCARE AG | 2010-06-30 | — | — | CN | disclosed |