Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 15/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 15/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955245 | 0.84 | KCNH2 (0.40) | TOP2ATOP2BKCNH2ALDH1A1LMNA | |
| SCHEMBL2825324 | 0.81 | KCNH2 (0.40) | TOP2ATOP2BKCNH2ALDH1A1LMNA | |
| SCHEMBL4248699 | 0.79 | TOP2A (0.33) | TOP2ATOP2B | |
| SCHEMBL2081014 | 0.78 | TOP2A (0.56) | TOP2ATOP2BKCNH2ALDH1A1LMNA | |
| SCHEMBL14387521 | 0.75 | KCNH2 (0.46) | TOP2ATOP2BKCNH2ALDH1A1 | |
| SCHEMBL9416458 | 0.75 | KCNH2 (0.41) | TOP2ATOP2BKCNH2ALDH1A1 | |
| SCHEMBL4208120 | 0.75 | TOP2A (0.53) | TOP2ATOP2BKCNH2ALDH1A1LMNA | |
| SCHEMBL13945289 | 0.75 | ADRB2 (0.43) | TOP2ATOP2BKCNH2ALDH1A1 | |
| SCHEMBL178589 | 0.74 | TOP2A (0.41) | TOP2ATOP2BALDH1A1 | |
| SCHEMBL9148042 | 0.73 | ADRB2 (0.55) | TOP2ATOP2BKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |