Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 9/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.67 |
| ▸ | HNF4A | P41235 | 2/20 | 0.67 |
| ▸ | DHFR | P00374 | 1/20 | 0.67 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.64 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | LDHB | P07195 | 1/20 | 0.52 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | UNG | P13051 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676105 | 1.00 | ACMSD (0.68) | ACMSDMCL1HNF4ADHFRTRIM24 | |
| SCHEMBL2560683 | 0.87 | ACMSD (0.67) | ACMSDMCL1HNF4ADHFRTRIM24 | |
| SCHEMBL6619210 | 0.85 | TRIM24 (0.57) | ACMSDMCL1HNF4ADHFRTRIM24 | |
| SCHEMBL29955613 | 0.85 | ACMSD (0.68) | ACMSDMCL1HNF4ADHFRLCK | |
| SCHEMBL31312290 | 0.83 | TRIM24 (0.62) | ACMSDMCL1HNF4ADHFRTRIM24 | |
| SCHEMBL2558013 | 0.83 | TRIM24 (0.62) | ACMSDMCL1HNF4ADHFRTRIM24 | |
| SCHEMBL2560594 | 0.83 | TRIM24 (0.62) | ACMSDMCL1HNF4ADHFRTRIM24 | |
| SCHEMBL28677845 | 0.82 | ERN1 (0.56) | ACMSDMCL1HNF4ADHFRTRIM24 | |
| SCHEMBL23143193 | 0.81 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRLCK | |
| SCHEMBL9273036 | 0.81 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |