Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.62 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.62 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.49 |
| ▸ | UNG | P13051 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560594 | 1.00 | TRIM24 (0.62) | TRIM24TRIM33ERCC5FEN1GRIK1 | |
| SCHEMBL2554092 | 0.88 | TRIM24 (0.62) | TRIM24TRIM33ERCC5FEN1UNG | |
| SCHEMBL2555818 | 0.85 | GRIK1 (0.53) | TRIM24TRIM33ERCC5FEN1GRIK1 | |
| SCHEMBL29954973 | 0.83 | ACMSD (0.68) | TRIM24TRIM33UNGCA12CA1 | |
| SCHEMBL28676105 | 0.83 | ACMSD (0.68) | TRIM24TRIM33UNGCA12CA1 | |
| SCHEMBL122520 | 0.81 | ACMSD (0.63) | ERCC5FEN1GRIK1GRIA1GRIA2 | |
| SCHEMBL7445345 | 0.81 | ALDH1A1 (0.59) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL2558013 | 0.81 | TRIM24 (0.62) | TRIM24TRIM33UNGCA12CA1 | |
| SCHEMBL2771204 | 0.81 | ALDH1A1 (0.68) | ERCC5FEN1GRIK1GRIA1GRIA2 | |
| SCHEMBL2553500 | 0.81 | TRIM24 (0.54) | TRIM24TRIM33UNGCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024263563-A1 | METABOTROPIC GLUTAMATE SUBTYPE-2 AND -3 RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-12-26 | — | — | WO | disclosed |