Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30322789 | 0.76 | PARP1 (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12396542 | 0.76 | PARP1 (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12023644 | 0.73 | CCR1 (0.57) | MAPTKDM4E | |
| SCHEMBL28561892 | 0.72 | HSP90AA1 (0.40) | ADORA3PARP1MAPTKDM4E | |
| SCHEMBL20982021 | 0.71 | AURKA (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3719247 | 0.69 | CA1 (0.42) | MAPTKDM4E | |
| SCHEMBL19988523 | 0.69 | ADORA3 (0.54) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21157142 | 0.69 | KIF11 (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19988521 | 0.67 | ADORA3 (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12590228 | 0.67 | GABRA1 (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |