Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PARG | Q86W56 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 5/20 | 0.51 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520306 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNAKMT2ATDP1PARG | |
| SCHEMBL2411241 | 0.81 | SMN1; SMN2 (0.61) | ALDH1A1LMNAKMT2ATDP1PARG | |
| SCHEMBL11992039 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAKMT2ATDP1PARG | |
| SCHEMBL21240889 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2ATDP1PARG | |
| SCHEMBL7144241 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2ATDP1PARG | |
| SCHEMBL2854064 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2ATDP1PARG | |
| SCHEMBL15688099 | 0.77 | CTSL (0.64) | ALDH1A1LMNAKMT2ATDP1PARG | |
| SCHEMBL2192047 | 0.76 | KDM4E (0.54) | ALDH1A1LMNAKMT2ATDP1PARG | |
| SCHEMBL2192046 | 0.76 | KDM4E (0.54) | ALDH1A1LMNAKMT2ATDP1PARG | |
| SCHEMBL3940478 | 0.76 | LMNA (0.76) | ALDH1A1LMNAKMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104079-A1 | SALICYLIC ACID AND PICOLINIC ACID DERIVATIVES AS INHIBITORS OF ENERGY COUPLING FACTOR (ECF) TRANSPORTERS FOR THE TREATMENT OF BACTERIAL INFECTIONS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2025-05-22 | — | — | WO | disclosed |
| CN-118339145-A | Bicyclic fused ring derivatives or salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-12 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |