SCHEMBL29954986

SCHEMBL29954986

OB(O)c1ccc(-c2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.61
CA2 P00918 3/20 0.52
MGLL Q99685 2/20 0.52
CA1 P00915 2/20 0.52
CYP1B1 Q16678 1/20 0.52
ENPP2 Q13822 2/20 0.50
KMO O15229 1/20 0.46
TTR P02766 1/20 0.44
SCN9A Q15858 1/20 0.41
ESR2 Q92731 2/20 0.41
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28393591 1.00 AHR (0.61) AHRCA2MGLLCA1CYP1B1
SCHEMBL28424779 0.82 CA2 (0.47) AHRCA2MGLLCA1ENPP2
SCHEMBL130450 0.81 TTR (0.61) AHRCA2CA1ENPP2TTR
Boric Acid SCHEMBL30873596 0.78 AHR (0.61) AHRCA2MGLLCA1CYP1B1
SCHEMBL13667445 0.78 CA2 (0.78) CA2MGLLCA1ENPP2TSHR
SCHEMBL18394607 0.78 CA2 (0.78) CA2MGLLCA1ENPP2TSHR
SCHEMBL806835 0.78 CA2 (0.78) CA2MGLLCA1ENPP2TSHR
SCHEMBL29769221 0.78 AHR (1.00) AHRCYP1B1KMOSCN9AESR2
SCHEMBL137915 0.78 AHR (1.00) AHRCYP1B1KMOSCN9AESR2
SCHEMBL1954438 0.77 ENPP2 (0.84) AHRCA2MGLLCA1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed