Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704768 | 1.00 | TYR (0.59) | TYRAKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL693837 | 1.00 | TYR (0.59) | TYRAKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL59197 | 0.84 | PTGS2 (0.74) | AKR1C3AKR1C2PTGS2PTGS1LMNA | |
| SCHEMBL11471204 | 0.82 | AKR1C3 (0.59) | TYRAKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL11434457 | 0.82 | PTGS2 (0.55) | AKR1C3AKR1C2PTGS2PTGS1LMNA | |
| SCHEMBL1140292 | 0.82 | TYR (0.57) | TYRAKR1C3AKR1C2PTGS2ALDH1A1 | |
| SCHEMBL11434458 | 0.82 | PTGS2 (0.55) | AKR1C3AKR1C2PTGS2PTGS1LMNA | |
| SCHEMBL6775188 | 0.82 | PTGS2 (0.64) | AKR1C3AKR1C2PTGS2PTGS1LMNA | |
| SCHEMBL9420395 | 0.82 | PTGS2 (0.55) | AKR1C3AKR1C2PTGS2PTGS1LMNA | |
| SCHEMBL1346361 | 0.82 | PTGS2 (0.55) | AKR1C3AKR1C2PTGS2PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |