Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21223556 | 0.84 | MAPT (0.54) | MCHR1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1642006 | 0.78 | ALOX5 (0.50) | MAPTRAB9ALMNAALOX5GAA | |
| SCHEMBL29954934 | 0.78 | MAPT (0.38) | MAPTCYP1A2CYP2C9CYP2C19NCEH1 | |
| SCHEMBL29956903 | 0.78 | ALOX5 (0.50) | MAPTRAB9ALMNAALOX5GAA | |
| SCHEMBL15331311 | 0.78 | SLC2A1 (0.49) | MAPTCYP1A2CYP2C9CYP2C19DHODH | |
| SCHEMBL1004416 | 0.76 | MAPT (0.58) | MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9477167 | 0.76 | MCHR1 (0.54) | MCHR1CYP1A2CYP2C19SMN1; SMN2NR2E1 | |
| SCHEMBL29517404 | 0.76 | MAPT (0.58) | MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29956003 | 0.76 | CNR1 (0.51) | MCHR1CYP2C9GAATDP1L3MBTL1 | |
| SCHEMBL2562676 | 0.75 | TLR8 (0.44) | MCHR1MAPTLMNANR2E1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |