Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21223556 | 0.83 | MAPT (0.54) | MAPTALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL29954994 | 0.78 | MCHR1 (0.43) | MAPTLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29517404 | 0.77 | MAPT (0.58) | MAPTMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL1004416 | 0.77 | MAPT (0.58) | MAPTMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL29954753 | 0.77 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15191879 | 0.74 | NCEH1 (0.48) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL29953987 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16718701 | 0.74 | NCEH1 (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15564688 | 0.73 | PRMT5 (0.41) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29956903 | 0.73 | ALOX5 (0.50) | MAPTALDH1A1KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |