Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955747 | 0.80 | GAA (0.56) | ALDH1A1L3MBTL1HTTGAATSHR | |
| SCHEMBL15330010 | 0.80 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1HTTGAATSHR | |
| SCHEMBL29952488 | 0.73 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1HTTGAATSHR | |
| SCHEMBL29952511 | 0.72 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1HTTGAATSHR | |
| SCHEMBL15330157 | 0.71 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1GAAKDM4EMAPT | |
| SCHEMBL15332332 | 0.69 | POLB (0.36) | ALDH1A1HTTTSHRMEN1KMT2A | |
| SCHEMBL29955058 | 0.69 | GAA (0.49) | ALDH1A1L3MBTL1HTTGAATSHR | |
| Urea SCHEMBL23160877 | 0.67 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1HTTGAATSHR | |
| SCHEMBL4667657 | 0.66 | ALDH1A1 (0.46) | ALDH1A1HTTTSHRMAPTNPC1 | |
| SCHEMBL3048491 | 0.66 | GAA (1.00) | ALDH1A1L3MBTL1HTTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |