Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955345 | 0.91 | KDM4E (0.60) | ALDH1A1KDM4ERAB9AHPGDTRIM24 | |
| SCHEMBL29957035 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4ERAB9AHDAC8HPGD | |
| SCHEMBL2554393 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9AHDAC8HPGD | |
| SCHEMBL2560889 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4ERAB9AHDAC8HPGD | |
| SCHEMBL12744692 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HPGDTSHRLY96CNR1 | |
| SCHEMBL8154071 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4ERAB9AHDAC8HPGD | |
| SCHEMBL29957119 | 0.82 | MAPT (0.58) | ALDH1A1KDM4ERAB9AHDAC8HPGD | |
| SCHEMBL2556331 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4ERAB9AHDAC8HPGD | |
| SCHEMBL29954807 | 0.81 | ALDH1A1 (0.57) | ALDH1A1RAB9AHPGDTSHR | |
| SCHEMBL21601619 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4ERAB9AHDAC8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |