Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332397 | 0.90 | KDM4E (0.56) | ALDH1A1RAB9AKDM4ETRIM24TYR | |
| SCHEMBL29952430 | 0.90 | RAB9A (0.72) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL29953639 | 0.88 | KDM4E (0.54) | ALDH1A1RAB9AKDM4ELY96TSHR | |
| SCHEMBL29955065 | 0.87 | ALDH1A1 (0.52) | ALDH1A1RAB9AKDM4ETRIM24TYR | |
| SCHEMBL29958149 | 0.87 | ALDH1A1 (0.51) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL15331330 | 0.86 | ALDH1A1 (0.58) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL2561319 | 0.86 | RAB9A (0.52) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL2559590 | 0.86 | RAB9A (0.55) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL29957274 | 0.86 | RAB9A (0.52) | ALDH1A1RAB9AKDM4ENPC1TRIM24 | |
| SCHEMBL15330145 | 0.86 | HPGD (0.55) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |