Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | QRFPR | Q96P65 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952289 | 0.87 | KMT2A (0.49) | KMT2AALDH1A1SMN1; SMN2QRFPR | |
| SCHEMBL29952913 | 0.82 | PARP14 (0.40) | PARP14KMT2A | |
| SCHEMBL29953460 | 0.79 | QRFPR (0.44) | PARP14PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL29950770 | 0.78 | PDE4D (0.44) | HTTMEN1CYP2C19KMT2APDE4D | |
| SCHEMBL29954864 | 0.75 | KMT2A (0.42) | PARP14KMT2A | |
| SCHEMBL29950900 | 0.73 | ENPP2 (0.46) | PARP14ALDH1A1QRFPR | |
| SCHEMBL31063056 | 0.72 | CA1 (0.44) | HTTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29953719 | 0.71 | PARP14 (0.45) | PARP14 | |
| SCHEMBL29951427 | 0.70 | LIPG (0.38) | PARP14 | |
| SCHEMBL15330913 | 0.69 | HTT (0.62) | HTTKMT2APDE4BALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |