SCHEMBL29952913

SCHEMBL29952913

OB(O)c1cc(CSC2CCOCC2)ccc1F

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 17/20 0.40
KMT2A Q03164 1/20 0.37
CCR2 P41597 1/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955087 0.82 PARP14 (0.41) PARP14KMT2A
SCHEMBL29954864 0.77 KMT2A (0.42) PARP14KMT2A
SCHEMBL29953719 0.76 PARP14 (0.45) PARP14
SCHEMBL20605181 0.76 PARP1 (0.41) POLB
SCHEMBL29950900 0.75 ENPP2 (0.46) PARP14KDM4E
SCHEMBL29953431 0.74 GPR84 (0.36)
SCHEMBL29956088 0.73 PARP14 (0.38) PARP14
SCHEMBL20605142 0.71 HRH3 (0.51)
SCHEMBL29951427 0.71 LIPG (0.38) PARP14
SCHEMBL29951557 0.68 RAB9A (0.43) KMT2AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed