Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 4/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17506332 | 0.79 | CCR1 (0.42) | CCR1CCR5CCR8ERN1TRIM24 | |
| SCHEMBL29954308 | 0.74 | CCR1 (0.41) | CCR1CCR5CCR8NOS3NOS2 | |
| SCHEMBL22350973 | 0.74 | CCR1 (0.48) | CCR1CCR5CCR8NOS3NOS2 | |
| SCHEMBL1491842 | 0.74 | NOS2 (0.42) | NOS3NOS2TLR7NOS1HTT | |
| SCHEMBL28260284 | 0.73 | TDP1 (0.41) | ERN1TRIM24TRIM33 | |
| SCHEMBL9207153 | 0.72 | CCR1 (0.47) | CCR1CCR5CCR8NOS3NOS2 | |
| SCHEMBL21856017 | 0.72 | NOS3 (0.41) | NOS3NOS2TLR7NOS1HTT | |
| SCHEMBL29506010 | 0.72 | NOS3 (0.41) | NOS3NOS2TLR7NOS1HTT | |
| SCHEMBL12480470 | 0.72 | CCR1 (0.42) | CCR1CCR5CCR8ERN1TRIM24 | |
| SCHEMBL3945531 | 0.71 | NOTUM (0.39) | NOS3NOS2NOS1USP7LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |