Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 11/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CFB | P00751 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955452 | 0.91 | OPRK1 (0.40) | OPRK1OPRM1OPRD1KCNH2CFB | |
| SCHEMBL29955663 | 0.80 | GAA (0.46) | OPRK1OPRM1OPRD1MEN1KMT2A | |
| SCHEMBL29954066 | 0.78 | ALDH1A1 (0.45) | OPRK1OPRM1OPRD1KCNH2DRD2 | |
| SCHEMBL2562106 | 0.78 | CYP2D6 (0.45) | OPRK1OPRM1OPRD1KCNH2MEN1 | |
| SCHEMBL29952091 | 0.77 | ALDH1A1 (0.44) | OPRK1OPRM1OPRD1KCNH2DRD2 | |
| SCHEMBL2555414 | 0.75 | SMN1; SMN2 (0.43) | OPRM1 | |
| SCHEMBL16380633 | 0.69 | ALDH1A1 (0.48) | KCNH2DRD2HTR2AHTR2CMEN1 | |
| SCHEMBL4260815 | 0.69 | CYP2A13 (0.54) | MEN1KMT2A | |
| SCHEMBL16380724 | 0.69 | ALDH1A1 (0.48) | MEN1KMT2AADRB2 | |
| SCHEMBL22944169 | 0.69 | OPRM1 (0.36) | OPRK1OPRM1OPRD1KCNH2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |