Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116160 | 1.00 | MAPT (0.43) | MAPTNPC1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL115669 | 0.86 | SIGMAR1 (0.43) | NPC1 | |
| SCHEMBL29953762 | 0.83 | MEN1 (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL115750 | 0.83 | MEN1 (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL20605142 | 0.77 | HRH3 (0.51) | MAPTNPC1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29790035 | 0.76 | HRH3 (0.38) | MAPTNPC1ALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL20896620 | 0.76 | HRH3 (0.38) | MAPTNPC1ALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL115588 | 0.74 | IDO1 (0.44) | MAPTTP53 | |
| SCHEMBL31002264 | 0.74 | HRH3 (0.44) | MAPTNPC1SMN1; SMN2HRH3MCHR1 | |
| SCHEMBL31082081 | 0.74 | HRH3 (0.51) | MAPTNPC1ALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |