Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115750 | 1.00 | MEN1 (0.49) | MEN1KMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL116160 | 0.83 | MAPT (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL29955596 | 0.83 | MAPT (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL115588 | 0.74 | IDO1 (0.44) | — | |
| SCHEMBL12311146 | 0.73 | LPL (0.36) | KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL114470 | 0.71 | KDM4E (0.53) | MEN1KMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL115669 | 0.69 | SIGMAR1 (0.43) | POLB | |
| SCHEMBL20037810 | 0.68 | POLB (0.57) | KDM4EPOLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL28588829 | 0.68 | MEN1 (0.69) | MEN1KMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL5784103 | 0.67 | KDM4E (0.68) | MEN1KMT2AKDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |