Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PON1 | P27169 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178969 | 1.00 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL911098 | 0.80 | ALDH1A1 (0.68) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29952420 | 0.80 | ALDH1A1 (0.68) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL12174817 | 0.76 | PTPN1 (0.67) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29951299 | 0.76 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBPOLB | |
| SCHEMBL23707495 | 0.76 | PTPN1 (0.67) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL177572 | 0.76 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL13978663 | 0.76 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBPOLB | |
| SCHEMBL5363245 | 0.76 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL11880267 | 0.76 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |