Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 5/20 | 0.60 |
| ▸ | MAOB | P27338 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025708 | 0.93 | PTPN1 (0.86) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL15898959 | 0.88 | PTPN1 (0.78) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29958044 | 0.87 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29952420 | 0.80 | ALDH1A1 (0.68) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL12174817 | 0.80 | PTPN1 (0.67) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL23707495 | 0.80 | PTPN1 (0.67) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29951299 | 0.80 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBKMT2A | |
| SCHEMBL13978663 | 0.80 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBKMT2A | |
| SCHEMBL911098 | 0.80 | ALDH1A1 (0.68) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL177572 | 0.80 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466915-A | Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof | 江西科技师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-117285925-A | Ratio fluorescence and colorimetric dual-mode reagent for detecting ethylenediamine based on electron energy transfer mechanism | 中国科学院新疆理化技术研究所 | 2023-12-26 | — | — | CN | claimed |
| US-3984441-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-10-05 | — | — | US | claimed |
| CN-115819431-B | Synthesis method and application of benzopyrone condensed hydroindole compounds | 广州大学 | 2025-06-24 | — | — | CN | disclosed |
| CN-119977949-A | Chromone bisindole derivative and preparation method and application thereof | 重庆文理学院 | 2025-05-13 | — | — | CN | disclosed |
| CN-119930565-A | Hydroxy flavonoid derivative and preparation method and application thereof | 重庆文理学院 | 2025-05-06 | — | — | CN | disclosed |
| CN-117466915-A | Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof | 江西科技师范大学 | 2024-01-30 | — | — | CN | disclosed |
| EP-4306106-A1 | NITRO-CONTAINING COMPOUNDS, COMPOSITIONS AND USES THEREOF | Universidade de Aveiro (PT) | 2024-01-17 | — | — | EP | disclosed |
| CN-117285925-A | Ratio fluorescence and colorimetric dual-mode reagent for detecting ethylenediamine based on electron energy transfer mechanism | 中国科学院新疆理化技术研究所 | 2023-12-26 | — | — | CN | disclosed |
| CN-115322192-B | Pyrrolo [3,4-b ] pyridine derivative and synthetic method and application thereof | 重庆文理学院 | 2023-07-14 | — | — | CN | disclosed |
| CN-115819431-A | Synthesis method and application of benzopyrone-fused hydrogenated indole compound | 广州大学 | 2023-03-21 | — | — | CN | disclosed |
| US-20120316192-A1 | SUBSTITUTED INDOLO [2,3-A] QUINOLIZINES | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-12-13 | — | — | US | disclosed |
| EP-2532664-A1 | Substituted indolo [2,3-a] quinolizines in the treatment of cancer | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2012-12-12 | — | — | EP | disclosed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-04 | — | — | US | disclosed |
| US-7202265-B2 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-20050197382-A1 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. | 2005-09-08 | — | — | US | disclosed |
| US-6506763-B2 | Useful in prevention and treatment of protein kinase related disorders such as cancer | SUGEN, INC. | 2003-01-14 | — | — | US | disclosed |
| US-6133305-A | PREVENTION AND TREATMENT OF PROTEIN KINASE RELATED DISORDERS SUCH AS CANCER | SUGEN, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| WO-2000053313-A2 | LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES | ARQULE, INC. (US) | 2000-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316192-A1 | SUBSTITUTED INDOLO [2,3-A] QUINOLIZINES | BOD1L1, ACIN1, CDC25C | PTPN1 1437/4885PTPN2 1096/4885MAOA 1610/4885 |
| US-20080300298-A1 | Honokiol Derivates For the Treatment of Proliferative Disorders | CCNK, CDK3, CCNO | PTPN1 3779/4885PTPN2 2735/4885MAOA 4495/4885 |
| US-20050197382-A1 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | FRK, PTK2, DSTYK | PTPN1 882/4885PTPN2 1051/4885MAOA 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.