Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CASP9 | P55211 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957984 | 0.85 | HTT (0.37) | HTTALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL13827600 | 0.80 | HTT (0.45) | HTTALDH1A1LMNAL3MBTL1RECQL | |
| SCHEMBL29952437 | 0.79 | HTT (0.40) | HTTALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL29952038 | 0.76 | HTT (0.34) | HTTALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL2555142 | 0.74 | HTT (0.71) | HTTALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL3089372 | 0.71 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4ENPC1POLB | |
| SCHEMBL29952455 | 0.71 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4ENPC1POLB | |
| SCHEMBL1671889 | 0.71 | HTT (0.42) | HTTALDH1A1LMNARECQLKDM4E | |
| SCHEMBL9843905 | 0.71 | HTT (0.38) | HTTALDH1A1L3MBTL1RECQLNPC1 | |
| SCHEMBL28330923 | 0.71 | NOS2 (0.50) | HTTMAPTNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |