Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SORD | Q00796 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957984 | 0.82 | HTT (0.37) | HTTLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL29955735 | 0.79 | HTT (0.35) | HTTLMNAKDM4EALDH1A1POLB | |
| SCHEMBL2555142 | 0.79 | HTT (0.71) | HTTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11981610 | 0.79 | HTT (0.52) | HTTHSD17B10LMNASORDMEN1 | |
| SCHEMBL29952038 | 0.78 | HTT (0.34) | HTTHSD17B10LMNAKDM4EALDH1A1 | |
| SCHEMBL29956524 | 0.74 | ERN1 (0.35) | HTTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL29952455 | 0.73 | ALDH1A1 (0.36) | HSD17B10LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL3089372 | 0.73 | ALDH1A1 (0.36) | HSD17B10LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL6119931 | 0.69 | NOS2 (0.46) | HTTHSD17B10SORDMEN1KMT2A | |
| SCHEMBL20851224 | 0.69 | HTT (0.39) | HTTHSD17B10LMNASORDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |