SCHEMBL3048491

SCHEMBL3048491

CN(C)c1ccc(C=O)o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 1.00
ALDH1A1 P00352 9/20 0.62
HTT P42858 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
MAPT P10636 5/20 0.42
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
KDM4E B2RXH2 4/20 0.42
TSHR P16473 1/20 0.42
USP2 O75604 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PKM P14618 2/20 0.41
POLB P06746 4/20 0.40
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ENPP1 P22413 1/20 0.37
CYP2A6 P11509 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7653003 0.77 ALDH1A1 (1.00) GAAALDH1A1HTTL3MBTL1MAPT
SCHEMBL51391 0.74
SCHEMBL29955747 0.73 GAA (0.56) GAAALDH1A1HTTL3MBTL1MAPT
SCHEMBL24089694 0.72 GAA (0.54) GAAALDH1A1HTTL3MBTL1MAPT
SCHEMBL28562831 0.72 ALDH1A1 (0.54) GAAALDH1A1HTTL3MBTL1MAPT
SCHEMBL28571795 0.72 ALDH1A1 (0.54) GAAALDH1A1HTTL3MBTL1MAPT
SCHEMBL28576319 0.72 ALDH1A1 (0.54) GAAALDH1A1HTTL3MBTL1MAPT
SCHEMBL28562313 0.72 ALDH1A1 (0.54) GAAALDH1A1HTTL3MBTL1MAPT
SCHEMBL28568742 0.72 ALDH1A1 (0.54) GAAALDH1A1HTTL3MBTL1MAPT
SCHEMBL28556905 0.72 ALDH1A1 (0.54) GAAALDH1A1HTTL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
WO-2023238683-A1 NOVEL HETEROCYCLIC COMPOUND AND SALT THEREOF, AND LUMINESCENT SUBSTRATE COMPOSITION 国立大学法人電気通信大学 2023-12-14 WO disclosed
US-11572351-B1 Bis-Schiff base compositions and formulations Systima Technologies, Inc. (US) 2023-02-07 US disclosed
US-11028194-B1 Bis-Schiff base compositions and formulations Jalapeno Holdings, LLC (US) 2021-06-08 US disclosed
US-20100278733-A1 COMPOSITION FOR DIAGNOSIS OF AMYLOID-RELATED DISEASE NAGASAKI UNIVERSITY (JP) 2010-11-04 US disclosed
US-20100278733-A1 COMPOSITION FOR DIAGNOSIS OF AMYLOID-RELATED DISEASE NAGASAKI UNIVERSITY (JP) 2010-11-04 US disclosed
EP-2030635-A1 COMPOSITION FOR DIAGNOSING AMYLOID-RELATED DISEASE Nagasaki University (JP) 2009-03-04 EP disclosed
EP-2030635-A1 COMPOSITION FOR DIAGNOSING AMYLOID-RELATED DISEASE Nagasaki University (JP) 2009-03-04 EP disclosed
WO-2000038641-A1 DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES L'OREAL (FR) 2000-07-06 WO disclosed
EP-0858262-A4 THROMBIN INHIBITORS MERCK & CO INC (US) 1998-12-02 EP disclosed
US-5798377-A ANTICOAGULANTS; PREVENTING THROMBUS FORMATION MERCK & CO., INC. (US) 1998-08-25 US disclosed
EP-0858262-A1 THROMBIN INHIBITORS Merck & Co., Inc. (US) 1998-08-19 EP disclosed
WO-1997015190-A1 THROMBIN INHIBITORS MERCK & CO., INC. (US) 1997-05-01 WO disclosed
US-5582962-A COLLOID LAYERS COMPRISING A DISPERSE DYE PARTICLES KONICA CORPORATION (JP) 1996-12-10 US disclosed
EP-0679935-A2 Silver halide photographic light-sensitive material and the processing method thereof KONICA CORPORATION (JP) 1995-11-02 EP disclosed
US-5340707-A Containing specified pyrazolone dye; storage stability KONICA CORPORATION (JP) 1994-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 GAA 4054/4885ALDH1A1 83/4885HTT 3885/4885
US-11028194-B1 Bis-Schiff base compositions and formulations FHIT, H1-0, H1-2 GAA 1450/4885ALDH1A1 859/4885HTT 1248/4885
US-11572351-B1 Bis-Schiff base compositions and formulations FHIT, H1-0, H1-2 GAA 1279/4885ALDH1A1 785/4885HTT 1344/4885
US-20100278733-A1 COMPOSITION FOR DIAGNOSIS OF AMYLOID-RELATED DISEASE APP, FABP7, APBA1 GAA 2094/4885ALDH1A1 2987/4885HTT 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.