Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25371038 | 0.81 | CA2 (0.41) | CA2CHKATRPV4PIK3CAPI4KB | |
| SCHEMBL14889731 | 0.78 | LMNA (0.36) | CA2CHKATRPV4PIK3CAPI4KB | |
| SCHEMBL31462730 | 0.78 | TRPV4 (0.34) | CA2CHKATRPV4ALDH1A1HSP90AA1 | |
| SCHEMBL30681544 | 0.78 | LMNA (0.36) | CA2CHKATRPV4PIK3CAPI4KB | |
| SCHEMBL3037202 | 0.76 | CA2 (0.50) | CA2CHKATRPV4PIK3CAPI4KB | |
| SCHEMBL29679747 | 0.76 | CA2 (0.50) | CA2CHKATRPV4PIK3CAPI4KB | |
| SCHEMBL17574541 | 0.76 | TDP1 (0.39) | CA2CHKATRPV4ALDH1A1ERN1 | |
| SCHEMBL31111318 | 0.76 | TDP1 (0.39) | CA2CHKATRPV4ALDH1A1ERN1 | |
| SCHEMBL29954476 | 0.75 | ERN1 (0.32) | ALOX5APFEN1ERN1 | |
| SCHEMBL18640592 | 0.74 | POLQ (0.35) | CA2CHKATRPV4ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |